UICOMP - Emergency Medicine Residency
  • Home
  • Faculty
    • Faculty Development
  • Residents
    • Forms
    • Inservice Exam
    • Education >
      • Conference Schedule 2015 - 2016 >
        • Conference Calendar
        • Book Review Readings
      • Advanced Airway Lab October 22, 2015
      • Emergency Medicine Educational Links
      • Journal Club
      • Research >
        • Research Project
        • Interesting Articles
      • Sim Lab >
        • Sim Lab Articles
      • Team STEPPS
      • Trauma CBL >
        • September 17, 2015
        • December 11, 2014
        • August 21, 2014
        • February 13, 2014
        • December 19, 2013
      • Ultrasound Review
    • Schedule >
      • Schedule Requests - Medrez
    • Rotation Objectives
    • Milestone Shift Cards
    • Interesting Articles
  • Students
    • Medical Student Rotation
  • Applicants
    • Peoria
    • Program Quick Facts
    • Residency Structure
    • 2015-2016 Academic Year Benefits
    • A Week in the Life
    • Prehospital >
      • EMS
      • EMS Track
      • Event and Disaster Medicine
      • Flight
      • Tactical Medicine
  • Meet the Team
    • Faculty
    • Class of 2015
    • Class of 2016
    • Class of 2017
    • Class of 2018
    • Where They've Gone
  • Contact Us
    • Program Coordinator
  • Blogs
    • Education
    • General Residency
  • Reunion
    • Alumni
    • Alumni Updates
    • RSVP

Dr. Timpe's Case Conference

3/23/2015

0 Comments

 
HPI
57 year old female with a history of cholecystectomy and hysterectomy presents with 2 days of chest pain and vomiting.  Yesterday the patient began to have epigastric pain that radiated to the midline chest.  Pain onset was at rest, constant, and not worsened with exertion.  She has had non-bloody emesis every 30 minutes since pain onset.  She is a non-smoker, no other cardiac risk factors.  She had a normal stress test in 2013 with a normal EF.  Father died of a MI at the age of 63.

ROS
Positive for subjective fever, rhinorrhea, chest pain, vomiting and abdominal pain.  Otherwise other pertinent ROS negative.

Exam
VS: BP 176/100, HR 97, RR 16, SpO2 96%, T98.5.
No acute distress.  Neck supple.  Regular rhythm, tachycardic, no murmur.  Normal breath sounds.  Symmetric distal pulses.  Abdomen is soft, tender to RUQ and epigastric area, no guarding or rebound tenderness.  Rectal exam normal, hemoccult negative.  Skin warm, dry.  No focal neuro deficits.

DDx:
  • MI
  • AAA/Dissection
  • Gastritis
  • PUD
  • Perforated Viscous
  • Cholangitis
  • Choledocholithiasis
  • Hepatitis
  • Pancreatitis
  • Obstruction
  • Mesenteric Ischemia

Course
Patient given ASA, NTG for chest pain.  She received IV zofran for nausea, IV fentanyl for pain.  SL NTG dropped SBP from 140 to 90, NTG subsequently withheld.  A bedside US showed a normal sized abdominal aorta.  EKG showed NSR, no acute ischemia, normal axis, no change from previous EKG two years prior.

Labs:  WBC 20, Hgb 14.6.  POC troponin 0.07 (mildly elevated).  AST 642, ALT 550, Alk Phos 136, t bili 2.3.
Lipase 6464 - leading to the diagnosis of pancreatitis.

The patient's pain was controlled and was  being prepared for admission.  Then, something went wrong....

The patient then became pale, tachycardic in the 140s, and has a syncopal episode in the ED.  A second large bore IV was placed and additional IV crystalloid fluids administered.  A repeat EKG shows no acute changes.  The patient wakes up after IVF bolus and is feeling better, HR improves and BP stabilizes.

A bedside US FAST exam is positive for fluid in the abdomen.  CT angio of the chest and abdomen showed a dissecting left hepatic artery pseudoaneurysm with hemorrhagic extension to the perihepatic, perisplenic and intraperitoneal left abdominal areas.  Repeat Hgb now 7.0 (previously 14.6), lactate 7.4.  The patient received stat PRBC infusion and general surgery was consulted.  Interventional radiology was consulted as well and the patient underwent embolization of the hepatic artery.

Outcome
The patient did well after the procedure and was discharged 1.5 weeks later, eventually diagnosed with Polyarteritis Nodosa.


Submitted by Dr. Josh Timpe, PGY-2

0 Comments

Sedation in Mechanically Ventilated Patients in the ED

3/12/2015

0 Comments

 
What is the best sedation for our intubated patients?
  • Classic sedation is using benzos, and then benzos, add some opioids, and more benzos!
  • We know that early deep sedation is associated with longer duration of vent support, higher need for tracheostomy, and increased mortality (SPICE I/II Trials).
  • Larsen et al. Systematic Review in 2013 showed that compared to a benzo sedative strategy, a non-benzo strategy was associated with a shortened ICU LOS (1.62 d) and duration of mechanical ventilation (1.9 d), but similar short-term mortality.

What non-benzos can be used for sedation??
Dexmedetomidine (Precedex)
  • Selective alpha-2 agonist
  • Causes sedation and analgesia
  • Decreases sympathetic tone - watch for bradycardia
  • Allows psychomotor function while patient rests comfortably
  • 2015 Cochrane Review showed 22% reduction in ventilator time and 14% reduction in ICU LOS compared to traditional sedative agents

Propofol (Diprivan)
  • Potentiates GABA-A receptor activity
  • Quick acting sedative with short half-life, easily titratable

What about no sedation?
  • Analgesia first is a viable and preferred option
  • Fentanyl, Morphine, Remifentanyl
  • Des Brown et al., 105 patients Multicenter study compared Remifentanyl only analgesia vs standard sedatives in ICU patients
  • Remifentanyl patients received midazolam as needed
  • Remifentanyl-based sedation reduced duration of mechanical ventilation by > 2 days
  • 26% did not require any midazolam, the remainder received less than the control group

Take Home Points
  • Early deep sedation is an independent predictor of increased on the ventilator, time in the ICU, and risk of death.  This is one factor we can potentially modify in the ED.
  • Focus on analgesia before adding sedative hypnotics
  • Attempt bolus dose anxiolytics before resorting to a continuous infusion
  • Ideally the patient should appear alert and calm, or be able to open his/her eyes to voice and make eye contact (RASS 0 to -1)
  • Dexmedetomidine and proposal are viable alternatives to benzodiazepines and are associated with reduced time on the ventilator and in the ICU


References
  1. Fraser G, et al. Benzodiazepine versus nonbenzodiazepine-based sedation for mechanically ventilated, critically ill adults: a systematic review and meta-analysis of randomized trials. CCM Journal 2013;41(9):S30-38.
  2. Wood S, Winters M. Care of the intubated emergency department patient. JEM 2011;40(4):419-427.
  3. Shehabi Y, et al. Early intensive care sedation predicts long-term mortality in ventilated critically ill patients. Am J Respire Crit Care Med 2012;186(8):724-731.
  4. Shehabi Y, et al. Sedation depth and long-term mortality in mechanically ventilated critically ill adults: a prospective longitudinal multi center cohort study. Intensive Care Med 2013;39:910-918.
  5. Strom T, Martinussen T, Toft P. A protocol for critically ill patients receiving mechanical ventilation: a randomized trial. Lancet 2010;375:475-80.
  6. Chen K, Lu Z, Xin YC, Cai Y, Chen Y, Pan SM. Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients. Cochrane Database of Systemic Reviews 2015, Issue 1. Art. No.: CD010269. DOI: 10.1002/14651858.CD010269.pub2.
  7. Breen D, et al. Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanyl with standard hypnotic-based sedation for up to 10 days in intensive care until patients: a randomized trial. Critical Care 2005;9:R200-210.
  8. Tanaka LM, Azevedo LC, Park M, Schettino G, Nassar AP Jr, Rea-Neto A, Tannous L, de Souza-Dantas VC, Torelly A, Lisboa T, Piras C, Carvalho FB, Maia MD, Gianini FP, Machado FR, Dal-Pizzol F, de Carvalho AG, Dos Santos RB, Tierno PF, Soares M, Salluh JI. Early sedation and clinical outcomes of mechanically ventilated patients: a prospective multicenter cohort study. Crit Care 2014, 18:R156.
  9. Gertler R, et al. Dexmedetomidine: a novel sedative-analgesic agent. Proc (Bayl Univ Med Cent). 2001 Jan; 14(1):13-21.

Submitted by Dr. Zach Radwine, PGY-3
0 Comments

Obstetrical Emergencies

3/12/2015

1 Comment

 
Case One: Postpartum Hemorrhage
25 yo G2P2 presents to the ED with continued vaginal bleeding s/p delivery.  She delivered her baby at home with the help of a midwife but has had prolonged vaginal bleeding for the past 4 hours after her delivery and was brought to the ED with orthostatic dizziness.  She has no significant past medical conditions and takes no medications.  Her vitals are HR 115, BP 95/65, RR 18, T 98.4F, pulse ox 99% RA.

What are the 4 "T's" that cause postpartum hemorrhage?
Tone, Trauma, Tissue, Thrombin

What are the key portions of the physical exam to help differentiate the causes of hemorrhage?
Uterine tone/bogginess, vaginal tears, placental exam (if available) to ensure entire placenta is present, uterine height or protruding uterus (uterine inversion)

How are vaginal tears classified?  Which types of vaginal tears require OB surgical repair?
1st degree - through vaginal mucosa
2nd degree - through vaginal muscular layer
3rd degree - into rectal sphincter
4th degree - through rectal mucosa
3rd and 4th degree tears require surgical repair

What diagnostic method is used to evaluate for retained products of conception?  Which findings have a high negative predictive value for retained products?  What is the treatment?
Ultrasound; empty or fluid filled uterus has a high negative predictive value.  Treatment is blunt digital dissection.  Further remnants are removed by curettage in the OR by OB.

What is the risk associated with forceful pulling of the umbilical cord during delivery?  What is the treatment of this complications?
Uterine inversion: before further removal of the placenta, pressure is applied to the uterine fundus through the introitus.  Tocolytics are used initial to relax uterine musculature then uterotonic agents (oxytocin) should be started once the uterus is appropriately repositioned.

What methods are available to the emergency physician to decrease further bleeding after tears and retained products have been evaluated for and bleeding continues?  What are the contraindications of prostaglandins and ergot alkaloids?  What may ultimately be required to treat postpartum hemorrhage?
A - Uterine massage
B - Uterotonic agents (oxytocin, prostaglandins, methergine).  Methergine/ergotamine can cause HTN (avoid in preeclampsia), F class prostaglandins are contraindicated in asthma.
C - Uterine packing using 15-20 yards of 4-inch packing gauze with ringed forceps in a layering fashion.
D - Hysterectomy (by OB)

Case Two: Abnormal Presentations
A 19 yo G3P2 presents to the ED in labor.  She is unsure of her gestational date as she has not seen an OB/Gy during the pregnancy and does not know her LMP.  She has been having regular contractions for an hour and had spontaneous rupture of membranes, which prompted her to come to the ED.  Her vitals are HR 101, BP 109/74, RR 16, T 99.1F, pulse ox 97% RA.

What needs to be done prior to taking the patient to labor and delivery?
Pelvic exam to determine stage of labor, dilation and effacement

You are able to see fetal crowning and prepare for emergent delivery and after delivery of the head you are unable to deliver a shoulder.  Which maneuvers are available to deal with shoulder dystocia?
Episiotomy
McRoberts' maneuver (maternal knee-to-chest postion)
Suprapubic pressure
Rubin's maneuver (pushing shoulders anteriorly)
Wood's corkscrew maneuver (accessible shoulder is rotated toward the chest and fetus is rotated 180 degrees)
Arm deliver (should be attempted last, hand is introduced posteriorly of the posterior arm, arm is swept across the chest and hand is brought toward the chin, splint the humerus and sweep the hand across the face)
HELPER mnemonic (call for Help, Episiotomy, Legs flexed, Pressure, Enter vagina, Remove posterior arm)

What is the proper technique for episiotomy?  What are the risks of each technique?
Mediolateral - 2% lidocaine local anesthesia, use tissue scissors to extend incision through the skin, subQ tissues and vaginal mucosa lateral to the anal sphincter.  Results in greater blood loss, repair is more difficult and healing is more painful.
Median - should be avoided due to extension into/through anal sphincter causing 3rd/4th degree lacerations.  Is easiest to repair, bleeds less, heals more rapidly with less pain and is preferred??? (per R&H)

What are the difference breech presentations?  Which presentations have the highest and lowest incidence of cord prolapse?  What is the method for safe breech deliver?
Frank - helps flexed, knees extended; 0.4% cord prolapse
Incomplete - hips and knees flexed; 5% cord prolapse
Complete - since or footling; 10% cord prolapse
For breech delivery, perform an episiotomy, deliver the posterior hip, then anterior hip by sweeping the legs away from the midline.  Then grab the pelvis with both hands with the thumbs on the sacrum and fingers on the ASIS.  Wrap the body in a towel and apply gentle downward pressure.  Rotate the fetus so the anterior shoulder is at the vulva then rotate in the reverse direction to deliver the other arm beneath the pubic symphysis.  Use the Maurice maneuver (place the index and middle fingers over the maxilla - NOT mandible - and the other hand over the fetal neck and apply gentle downward pressure) with assistance of suprapubic pressure to deliver the head.

How is umbilical cord prolapse managed?  Cord entanglement?
Umbilical cord prolapse - mother is placed in knee-to-chest position and bed in Trendelenburg and the presenting part is lifted off of the cord.  Emergent cesarean section should be performed, but if unavailable, the cord should be reduced and rapid vaginal delivery performed.
Cord entanglement - nuchal cords should be reduced at the perineum by slipping them over the head.  Loose body cords usually reduce spontaneously.  If loops are too tight to be reduced and impede delivery, then they should be cut and clamped with rapid fetal delivery.

Case Three: Postpartum Cardiomyopathy
A 31 yo G3P3 postpartum day 17 presents with exertional dyspnea and fatigue.  She had an uncomplicated vaginal delivery and has no significant past medical conditions.  She denies chest pain or history of PE and does not have a cough or significant symptoms at rest, but has been sleeping on 3 pillows at night to help with sleep.  Vitals are HR 89, BP 115/78, RR 18, T 98.2F, pulse ox 94% RA.

What is the incidence of postpartum cardiomyopathy and which populations are more at risk?  What is the typical time frame for onset?
1/4000 pregnancies are affected but may be more frequent due to missed milder forms.  PPCM is more common in African Americans and multiparous women.  Onset is usually days to weeks after delivery.

What are treatment options for PPCM during pregnancy?  After pregnancy?
Oxygen, diuretics (HCTZ), and vasodilators during pregnancy
ACE inhibitors and amlodipine after pregnancy

What is the natural sequela of PPCM?  How does this affect the recommendations for further pregnancies?
50% have normal cardiac function within 6 months, while some have residual deficits in function and have an 85% 5 year mortality rate.  It is generally recommended to avoid further pregnancies, though PPCM after one pregnancy does not predict recurrence in the future.

Submitted by Dr. Dan Montgomery
1 Comment

    Author

    Write something about yourself. No need to be fancy, just an overview.

    Archives

    January 2016
    November 2015
    October 2015
    September 2015
    August 2015
    July 2015
    June 2015
    May 2015
    April 2015
    March 2015

    Categories

    All

    RSS Feed

Website maintained by Mari Baker, updated 03/04/2016
✕